Additional Applications of Corneal Cross Linking

Additional Applications of Corneal Cross Linking

Corneal collagen cross-linking (CxL) is a prevalent surgical method for the management of keratoconus. However, literature suggests that, further to keratoconus, CxL has a beneficial impact on a series of corneal related diseases and states. This article attempts to provide a contemporary review for all additional applications of CxL. Specifically, it outlines the most recent studies that demon...

Corneal cross-linking.

Since its inception in the late 1990s, corneal cross-linking has grown from an interesting concept to a primary treatment for corneal ectatic disease worldwide. Using a combination of ultraviolet-A light and a chromophore (vitamin B2, riboflavin), the cornea can be stiffened, usually with a single application, and progressive thinning diseases such as keratoconus arrested. Despite being in clin...

Bonding corneal tissue: applications of photoactivated diazopyruvoyl cross-linking agent.

Photoactivated bis-diazopyruvamide-N,N'-bis(3-diazopyruvoyl)-2,2'-(ethylenedioxy)bis-(ethylamine), (DPD)-was previously shown to bond materials containing type I collagen. However, tensile strength of bonded collagenous tissue ( approximately 78% water) was low compared with that of dehydrated collagenous gelatin ( approximately 14% water). Here we investigated the role of water in corneal tiss...

Corneal collagen cross-linking: new and expanding applications.

Evaluation of Corneal Aberrometry Parameters Before and After Cross-Linking in Patients with Keratoconus

Background and Objective: In the last decade, cross-linking (CXL) has been widely used for treating people with progressive keratoconus. The present study aimed to compare corneal aberrometry parameters before and after CXL in patients with keratoconus. Materials and Methods: In this cross-sectional study, 67 patients with keratoconus referred to Farshchian Sina Medical Education Center, Hamad...